THE Graft™ Collagen block is composed of porcine-derived bone mineral matrix from cancellous bone and atelocollagen from the porcine tendon.
THE Graft™ Collagen is abone graft intended to fill, augment, and/or reconstruct periodontal, oral, and maxillofacial defects. THE Graft™ Collagen bone mineral matrix is similar to physical and chemical aspects of human bone mineralized matrix. Hydrated collagen components have a viscosity that facilitates for blending of bone mineral matrix.
With this characterization, THE Graft™ Collagen can be trimmed and/or molded to various defect shapes and can be fixed in bone defect sites. As time passes, THE Graft™ Collagen is partially transformed by the osteoclast and osteoblast cells.
WHY THE Graft™ Collagen?
While being manufactured, the structure of THE Graft™ is maintained and the shape of a matrix is preserved as the fibrous collagen holds the granules in place.
A high surface energy and porosity of Matrix ease the migration, adhesion, and growth of cells, which is helpful for bone regeneration and volume stability. Collagen promotes not only healing and regeneration but also hemostasis.
Consistency, safety, and effectiveness of products are ensured through overall quality control from raw material selection to the final product.
- High surface energy and interconnective pores allow to have high hydrophilicity.
- High hydrophilicity enables the absorbance of more blood and is advantageous for attracting proteins such as growth factors and cytokines needed for new bone regeneration.
THE Graft™ (porcine-derived Xenograft) + Type I Collagen
«Safety and purity are an important concern when using a biomaterial»
Easy Handling & Moldable
THE Graft™ Collagen is a moldable bone graft material due to its easy handling before and after hydration.
With excellent handling property, THE Graft™ Collagen can be adapted to each defect site with more ease.
Various Shapes & Sizes
THE Graft™ Collagen minimizes the risk of infection by using porcine-derived materials, which has a low risk of zoonosis processed through a proprietary manufacturing process (to eliminate antigens that can potentially cause an immune response and viruses).
Excellent Bone Remodeling
Balanced interconnective pores play a decisive role in the recruitment and penetration of cells from surrounding bone tissue as well as osteoconductivity in bone regeneration.
The high osteoconductivity of THE Graft™ Collagen allows rapid remodeling through osseointegration with new bone.
- THE Graft™ Collagen prevents the collapse of the introduced space for bone formation, providing space-making stability and volume maintenance.
Indications
- Management of contained extraction socket
- Management of non-contained extraction scoket
- Simultaneous augmentation
- Staged augmentation
- Sinus floor augmentation
- Periodontal defects
- Peri-implantitis
- Immediate implant
- Immediate implant
- Soft tissue volume
Info File
References
- [1] LEE, Jae-Hong; JUNG, Eun-Hee; JEONG, Seong-Nyum. Augmentation Stability of Guided Bone Regeneration for Peri- Implant Dehiscence Defects with L-shaped Porcine-Derived Block Bone Substitute. Materials, 2021, 14.21: 6580.
- [2] LEE, Jae-Hong; JEONG, Seong-Nyum. Use of Porcinederived Block Bone Substitutes for Guided Bone Regeneration in the Peri-implant Dehiscence Defects of the Mandibular Anterior Region. 2021
- [3] LEE, Jae‐Hong; JUNG, Eun‐Hee; JEONG, Seong‐Nyum. Profilometric, volumetric, and esthetic analysis of guided bone regeneration with L‐shaped collagenated bone substitute and connective tissue graft in the maxillary esthetic zone: A case series with 1‐year observational study. Clinical Implant Dentistry and Related Research, 2022, 24.5: 655-663.
- [4] U. Cheema, M. Ananta, V. Mudera. Collagen: Applications of a Natural Polymer in Regenerative Medicine. Regenerative Medicine and Tissue Engineering, 2011.
- [5] KY Jang, JH Lee, SH Oh, BD ham, SM Chung, JK Lee. Bone graft materials for current implant dentistry. Journal of Dental Implant Research 2020; 39(1): 1-10
- [6] Wahl, D.; Czernuszka, J. Collagen-Hydroxyapatite Composites for Hard Tissue Repair. Eur. Cells Mater. 2006, 11, 43–56.
- [7] Thunwa Binlateh, Peungchaleoy Thammanichanon, Pawornwan Rittipakorn, Natthapol Thinsathid, Paiboon Jitprasertwong. Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen. Biomimetics. 2022, 24;7(2):34.
- [8] Ryan, A.; Gleeson, J.P.; Matsiko, A.; Thompson, E.M.; O’Brien, F.J. Effect of different hydroxyapatite incorporation methods on the structural and biological properties of porous collagen scaffolds for bone repair. J. Anat. 2015, 227, 732–745.
THE Graft™ Collagen Demonstration
THE Graft™ Collagen Specifications
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